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尿激酶在外科肿瘤的研究进展 被引量:2

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摘要 uPA介导的纤溶系统与细胞外基质和基底膜的降解有关 ,在肿瘤的生长、浸润和转移过程中起重要作用。检测uPA系统各蛋白的水平可以作为判断肿瘤的恶性程度和预后的标记 ,特异性地阻止uPA/uPAR的活性、抑制uPA或uPAR的表达 ,可以抑制肿瘤的浸润和转移 。
作者 文博 杨为民
出处 《临床外科杂志》 2004年第2期115-117,共3页 Journal of Clinical Surgery
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