摘要
目的探讨火针对类风湿关节炎大鼠IL-1、IL-6的影响。方法以佐剂性关节炎(AA)作为类风湿关节炎大鼠模型,随机分为正常对照组、模型组、火针治疗组,火针“足三里”后,检测IL-1、IL-6含量变化。结果模型组大鼠腹腔巨噬细胞IL-1、IL-6的活性比正常大鼠明显升高(P<0.01),火针组大鼠IL-1、IL-6活性下降明显,与模型组比较,具有统计学意义,P<0.01。结论 火针可抑制从大鼠IL-1、IL-6活性。
Objective: To find out influence of hot needling on IL - 1 and IL - 6 in serum in rat with rheumatoid arthritis. Methods: Rats are grouped as normal group, model group and hot needling group. We take adjuvant arthritis as a model of rheumatoid arthritis. Rats in hot needling group were treated with hot needling on ST36(Zu sanli) and then we measured content of IL - 1 and IL - 6 in serum by EIJSA in all rats. Result: There is an apparent difference of content of IL - 1 andIL - 6 among three groups. Conclusion: Hot needling can reduce content of TNF- αin serum in rat with adjuvant arthritis.
出处
《成都中医药大学学报》
2004年第2期35-36,64,共2页
Journal of Chengdu University of Traditional Chinese Medicine
基金
国家自然科学基金资助(编号:39870956)
