老年与非老年大肠息肉对比分析

Comparative analysis to colorectal polyps of elder and the other patients

目的 :回顾分析有病理诊断的大肠息肉 ,更好地认识老年与非老年大肠息肉的差别。方法 :回顾整理连续 4年内资料完整可用的老年大肠息肉病例。分析指标包括性别、年龄、息肉部位、数目、是否有蒂、黏膜情况、是否分叶、病理类型、息肉大小、不典型增生程度和癌变等因素。采用卡方检验及逐步logistic分析。结果 :老年和非老年大肠息肉 (不含幼年性息肉 )在患者的性别 ,息肉的部位、是否有蒂、大小和不典型增生方面的差异有显著意义 ;老年与非老年患者大肠息肉癌变或不典型增生率只有在光滑息肉中的差别有统计学意义 ;单因素分析显示老年和非老年大肠息肉 (不含幼年性和错构性息肉 )癌变或不典型增生均在大小、黏膜情况、病理类型、是否分叶状等因素的差别有统计学意义 ,另外老年大肠息肉在部位的差别也有统计学意义 ;多因素逐步logistic分析显示 ,与老年和非老年息肉癌变或不典型增生独立相关的因素均为息肉的大小、病理类型、黏膜情况和是否有蒂。结论 :老年和非老年大肠息肉是有差别的 。

Objective:To retrospectively analysis the colorectal polyp difference of elder and other patients. Methods: Data on a total of 820 patients (900 polyps) who had undergone polypectomy between 1997 and 2001 at PLA General Hospital were collected. The difference of colorectal polyps of elder and other patients was assessed by Stata 4.0. Results:The differences (not include juvenile polyps) on sex of patients,sessile or pedunculated polyps,mucosal pathological changes,size and location of polyps,and grade of dysplasia were statistically significant. Canceration or dysplasia rat of polyp with normal mucosa was significantly different between elder and the other patients. Size,histology,sessile or pedunculated and mucosal pathological changes were the major independent polyp risk factors associated with canceration or dysplasia in both elder and other patients (not include juvenile and Peutz-Jeghers polyps). Conclution:there are some differences of polyps between elder and the other patients,but the major independent polyp risk factors associated with canceration or dysplasia are the same.