辐照氟银肌腱的生物力学和组织形态学变化

Biomedical and Morphological Study of γ-Irradiated Tendon Incorporated with Norfloxacin and Silver

目的 探讨辐照氟银肌腱的生物力学性质及形态学变化。方法 肌腱随机分为 3组 :辐照氟银肌腱 (A组 ) ,深低温冷冻肌腱 (B组 )与新鲜肌腱 (C组 )。观察各组生物力学及形态学组织学的变化。结果 辐照氟银组最大载荷和抗张强度明显大于其它各组 (P <0 .0 1) ;组织形态学上各处理组均不同于正常肌腱 ,辐照氟银组光镜下几无细胞 ,纤维呈波浪形 ,深低温冷冻肌腱组细胞很少 ,纤维间距大。

Objective To explore the biomechanical and morphological characters of γ-Irradiated tendon incorporated with norfloxacin and silver immersion.Methods Tendons were randomly divided into three groups:irradiated allogeneic tendon incorporated with norfloxacin and silver group(Group A),deep-frozen allogeneic tendon group(Group B)and autogeneic tendon group(GroupC).Biomechanic or histology properties were observed.Results The ultimate tensile stress of Group A was markedly greater than that of Group B and C(P<0.01).All treated tendons differed considerably from the normal tendon in histological.γ-Irradiated tendons had no cellularity, but had a larger amplitude,pitch of crimp,and wider interfibrillar spaces than normal tendons.The deep-frozen tendons also showed less cellularity and had wider interfibrillar spaces.Conclusion γ-Irradiated tendon incorporated with norfloxacin and silver immersion may be used to allogeneic grafts.