2次与3次痰涂片对初治涂阳肺结核患者痰菌阴转结果的比较

Comparison on the smear negative conversion rates of new smear positive TB cases through 2 sputum smear tests and 3 sputum tests

目的 了解 2次痰涂片与 3次痰涂片法考核初治涂阳肺结核患者痰菌阴转结果的差异。方法 对 10 4 7例初治涂阳肺结核患者 ,在 6月的治疗期间每月用 2次痰涂片和 3次痰涂片法查痰 1次。对治愈患者中的 998例进行了 2年的随访查痰。结果 在 6月治疗期间 ,治疗后 4～ 6月末的痰菌阴转率 2次痰涂片法和 3次痰涂片法几乎一致 ,差别较大的是在治疗头 1～ 2月 ,其痰菌阴转率分别相差 4 .4 %和 3.1%。 2月末 2次痰涂片法痰菌阴转 ,或未阴转但延长了 1月的强化期治疗者 ,与 2月末 2次痰涂片法痰菌阴转而 3次痰涂片法痰菌仍然阳性 ,但又未延长强化期治疗者的 2年细菌学复发率分别是 2 .4 %和 9.4 % ,经统计学处理有显著性差异意义。结论 涂片阳性肺结核患者治疗期间 1月末和 2月末的随访查痰应以

Objective To determine the difference on smear negative conversion rates of new smear positive TB patients by 2 smear tests and 3 smear tests.Methods Testswith 2 smear and 3 smear are conducted once a month in the six months of treatment of the new smear positive TB patient 1?047.Results During the six months of treatment,the smear negative conversion rates by 2 smear and 3 smear tests at the end of 4th～6th months of treatment are almost the same.The difference was found at the end of 1th and 2nd months.The differences was 4.4% and 3.1% respectively.The relapse rates within two years was 2.4% in cases with negative results and with intensive treatment for another month,and 9.4% in cases of negative result of 2 smear test at end of the 2nd month but still of positive result of 3 smear test and nit out extended intensive treatment.There was significant difference.Conclusion It is better to conduct follow up sputum tests at the end of month 1 and 2 of tre atment of TB patients by 3 smear tests.