巨乳症的临床与病理学观察

Clinicopathologic changes of gigantomastia

目的 研究巨乳症的临床与病理学特点。方法 采用免疫组化S P法测定 10例巨乳症组织中雌激素受体 (ER)、孕激素受体 (PR)的表达。结果 巨乳症乳腺组织光镜下以间质纤维组织、脂肪组织及血管增生为主 ,ER(+)或ER和PR(+)为75 %。

Purpose To study the clinical and pathologic changes in gigantomastia and the expression of estrogen and progesterone receptors. Methods Estrogen receptor and progesterone receptor were measured with immunohistochemical assay. Results Gigantomastia was consisted primarily of fat, fiber and vascular tissues under light microscope. The positive rates of estrogen receptor or estrogen and progesterone receptors were 75%. Conclusions The increase of breast's sensitivity to estrogen is associated with the occurrence of gigantomastia.