皮维碘灌注对肝胆系统形态及功能的影响

The effects of povidon-iodine irrigation on the morphology and function of hepatobiliary system of experiment study

目的 探讨 1.0 %及 2 .5 %皮维碘 (PVI)灌注于肝胆系统的可行性及安全性。方法青紫兰免 3 0只随机分 2组 ,分别用 1.0 %和 2 .5 %PVI经胆囊造瘘管灌注 ,手术前后抽血验肝、肾、甲状腺功能等作比较 ,取肝、胆囊等行病理学检查。结果 1.0 %及 2 .5 %PVI灌注对免肝、肾、甲状腺功能等无明显影响 ,对肝、胆囊、胆总管及十二指肠无明显病理损害。结论 1.0 %及 2 .5

Objective To study the feasible and safe of hepatobiliary System after infusion of 1.0% or 2.5% PVI into the biliary tract.Method 30 rabbits,randomize divided into two groups,inject 10 ml of 1.0% or 2.5% povidone Iodine (PVI) through the cholecystis.Pre and post opertive blood tests for the rule and function of the live,Kidney and thyroid are conducted to make a comparison,take a little tissue from the live and gallbladder to have pathological test.Result No obvious influence of 1.0% and 2.5% PVI infusion on the function of the live,the Kidney,the thyroid gland and blood Rbc?Wbe?PLA of rabbits was observed.No obvious pathological damage to the rabbits liver?gallbladder?common bile duct and duodenum after infusion of 1.0% or 2.5% PVI into the biliary tract was found.Conclusion It is the feasible and the safe of hepatobiliary System after infusion of 1.0% or 2.5% PVI into the biliary tract.