1Francesconi A, Duvoisin RM. Opposing effects of protein kinase C and protein kinase A on metabotropic glutamate receptor signaling:selective desensitization of the inositol trisphusphate/Ca2+ pathway by phosphorylation of the receptor-G protein-coupling d
2GROVER LM, YAN C. Evidence for involvement of group Ⅱ/Ⅲ metabotropic glutamate receptors in NMDA receptor-independent long-term potentiation in area CA1 of rat hippocampus[J]. J Neurophysiol, 1999, 82(6): 2956-2969.
3OZAWA S, KAMIYA H, TSUZUKI K. Glutamate receptors in the mammalian central nervous system[J]. Prog Neurobiol, 1998,54(5) :581-618.
4CALABRESI P, CENTONZE D, BERNARDI G. Cellular factors controlling neuronal vulnerability in the brain: a lesson from the striatum[J]. Neurology, 2000, 55(9):1249-1255.
5TAKUMI Y, BERGERSEN L, LANDSENDAS, et al. Synaptic arrangement of glutamate receptors[J]. Prog Brain Res, 1998,116:105-121.
6KULLMANN DM, ASZTELY F. Extrasynaptic glutamate spillover in the hippocampus: evidence and implications[J]. Trends Neurosci, 1998, 21(1):8-14.
7RIEDEL G. Function of metabotropic glutamate receptors in learning and memory[J]. Trends Neurosci, 1996, 19(6): 219-224.
8GEREAU RW 4th, HEINEMANN SF. Role of protein kinase C phosphorylation in rapid desensitization of metabotropic glutamate receptor 5[J]. Neuron, 1998, 20(1): 143-151.
9MANNAIONI G, MARINO MJ, VALENTI O, et al.Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function[J]. J Neurosci, 2001, 21 (16):5925-5934.
5KAWAHARA M. Effects of aluminum on the nervous system and its possible link with neurodegenerative diseases [ J ]. Alzheimer's Dis, 2005, 8(2): 171-182.
6沈鱼.神经病学[M].北京:人民卫生出版社,2001:2-41.
7YE Y, GUO JZ, ZHOU QX, et al. The homeostasis of iron and suppression of HO-1 involved in the protective effects of nimodipine on neurodegeneration induced by aluminum overloading in mice [ J ] .Eur JPharmacol, 2008, 586( 1-3 ): 100-105.
8MEYER-BARON M, SCHAPER M, KNAPP G, et al. Occupational aluminum exposure: Evidence in support of its neurobehavioral impact[ J ]. Neuro Toxicol, 2007, 28( 6 ): 1068-1078.
9YOKEL R A. Aluminum produces age related behavioral toxicity in the rabbits[ J ]. Neurotoxieol teratol, 1989, 11 ( 3 ): 237-242.
10YEN-KOO H G. The effect of aluminum on conditioned avoidance ( CAR )in mice[ J ]. Toxicol Ind Health, 1992, 8( 1-2 ): 1-7.
