液氮冷冻治疗鳞屑性睑缘炎的疗效观察

Observation on Therapeutic Effect of Squamous Blepharitis Treated with Liquefacient Nitrogen Cryotherapy

目的:观察液氮冷冻治疗鳞屑性睑缘炎的临床疗效。方法:选取近几年在我院就诊的鳞屑性睑缘炎患者126例234眼,随机分为液氮冷冻治疗观察组65例120眼,每周2-3次治疗,6～10次为一疗程,同时滴用抗生素眼液及眼膏;药物治疗对照组61例114眼,采用滴抗生素眼液及眼膏和2％黄降汞眼膏,20—25 d为一疗程,经治疗二疗程后进行疗效比较。结果:观察组治愈64眼,有效30眼,无效26眼。有效、无效者继续治疗一疗程后治愈32眼,总治愈率80％,对照组治愈48眼,有效30眼,无效36眼,总治愈率42.11％,经统计学处理(X2=-35.47,P<0.01),差异有显著性。结论:液氮冷冻治疗鳞屑性睑缘炎有明显的疗效。

Purpose:To observe the therapeutic effect of squamous blepharitis treated with liquefacient nitrogen cryotherapy. Methods: 126 patients (234 eyes) with squamous blepharitis were randomly divided into two groups. Observation group 65 patients (120 eyes) were treated with liquefacient nitrogen cryotherapy adding antibiotic eye drops and ointments. Control group 61 patients (114 eyes) were treated with antibiotic eye drops and 2% yellow mercury oxide ointments. Both groups were treated for two courses, 20~25 days per course. Results: sixty-four eyes of observation group were cured, 30 eyes were improved and 26 eyes were ineffective. Thirty-two eyes of improved and ineffective patients were cured after an additional course. Total cured rate was 80%. Fourty-eight eyes of control group were cured, 30 eyes were improved and 36 eyes were ineffective. Total cured rate was 42.11%. The difference of two groups were significant (X2=35.47, P<0.01). Conclusions : liquefacient nitrogen cryotherapy was an effective method for squamous blepharitis.