摘要
The pentadecanolide was biosynthesized in cyclohexane from 15-hydroxypentadecanoic acid, which as prepared from 15-tetracosenoic acid in Malania Olcifera Chum oil using lipase as catalyst. The effect of lipase activity on the lactonization was investigated. Lipases from fiften strains (13 strains of Candida and 2 strains of Penicillium) showed different catalytic effects to the synthesis reactions. The lipases from strains of Penicillium sp. and 4 strains of Candida sp. have catalytic lactonization activity, and the conversion ratio of substrate reached 88% by using lipase Candida sp.GXU01.
The pentadecanolide was biosynthesized in cyclohexane from 15-hydroxypentadecanoic acid, which as prepared from 15-tetracosenoic acid in Malania Olcifera Chum oil using lipase as catalyst. The effect of lipase activity on the lactonization was investigated. Lipases from fiften strains (13 strains of Candida and 2 strains of Penicillium) showed different catalytic effects to the synthesis reactions. The lipases from strains of Penicillium sp. and 4 strains of Candida sp. have catalytic lactonization activity, and the conversion ratio of substrate reached 88% by using lipase Candida sp.GXU01.
出处
《应用化学》
CAS
CSCD
北大核心
2004年第8期850-852,共3页
Chinese Journal of Applied Chemistry
基金
教育部科学技术重点项目资助 ( 2 0 4110 )
广西自然科学基金资助项目 (桂科自 0 13 5 0 13 )
关键词
环十五内酯
脂肪酶
羟基十五烷酸
cyclopentadecanolide,lipase,hydroxypentadecanoic acid
