期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

文昌鱼profilin同源基因的胚胎发育表达图式 被引量：1

EXPRESSION PATTERN OF PROFILIN HOMOLOGUE IN EMBRYOGENESIS OF AMPHIOXUS
下载PDF
导出
摘要 本研究利用胚胎整体原位杂交技术结合系列组织学切片技术,以及Northern blot 分析,对进化上处于特殊地位的模式动物文昌鱼profilin 基因不同发育时期的表达图式进行了系统研究,揭示了该基因的动态表达图式与肌肉分化的过程一致,文昌鱼profilin 基因可能与胚胎早期肌肉的发育相关。同时,通过Southern blot 检测对青岛文昌鱼profilin 基因可能存在的同源体进行了探讨,试图为弄清文昌鱼肌肉发育分化的分子机制提供资料。 The expression pattern of profilin homologue in embryogenesis of amphioxus wascharacterized by whole-monnt in situ hybridization combined serial histological sections andNorthern blot.The results revealed that the dynamic expression pattern of the profilin homo-logue just accorded with muscle differentiating in this animal.It was most possibly involved inthe development of muscle in amphioxus.The result of Southern blot supported that there wasonly one copy of profilin homologue in the genome of Qingdao amphioxus.It may be good for ex-plaining the molecular mechanism of muscle differentiation in amphioxus.
作者 张晓辉 杨卉 黄向炜 王利凤 陈忠科 张燕君 张培军 张红卫
机构地区 山东大学生命科学院发育生物学研究所 中科院青岛海洋研究所
出处 《实验生物学报》 CSCD 北大核心 2004年第4期283-288,共6页 Acta Biologiae Experimentalis Sinica
基金 国家自然科学基金(30070094 30270693) 山东省自然科学基金(L2000D03)资助
关键词 文昌鱼 PROFILIN 同源基因 胚胎发育 表达图式 肌肉 蛋白 profilin. Expression pattern. Development. Muscle. Amphioxus
分类号 Q954.4 [生物学—动物学]
  • 相关文献

参考文献20

  • 1Carlsson, L., L.E.Nystrom, I.Sundkvist, F.Markey & U.Lindberg, 1977, Actin polymerizability is influenced by profilin, a low molecular weight protein in non-muscle cells. J. Mol. Biol., 115: 465-483.
  • 2Carlier, M.F. 1998, Control of actin dynamics. Curr.Opin. Cell Biol., 10: 45-51.
  • 3Pantaloni, D. & M.F.Carlier, 1993, How profilin promotes actin filament assembly in the presence of thymosineb4.Cell, 75: 1007-1014.
  • 4Lassing, I. & U.Lindberg, 1985, Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin. Nature, 314: 472-474.
  • 5Goldschmidt-Clermont, P.J., L.M.Machesky, J.J.Baldassare & T.D.Pollard, 1990, The actin-binding protein profilin binds to PIP2 and inhibits its hydrolysis by phospholipase C. Science, 247: 1575-1578.
  • 6Michael, D.J., P.J.Hussey & B.Davies, 2002, Formins: intermediates in signal-transduction cascades that affect cytoskeletal reorganization. TRENDS in Plant Science, 7(11): 492-498.
  • 7Verheyen, E.M. & L.Cooley, 1994, Profilin mutations disrupt multiple actin-dependent processes during Drosophila development. Development, 120: 717-728.
  • 8Haarer, B.K., S.H.Lillie, A.E.Adams, V.Magdolen & W.Bandlow, 1990, Purification of profilin from Saccharomyces cerevisiae and analysis of profilin-deficient cells.J. Cell Biol., 110: 105-114.
  • 9Haarer, B.K., A.S.Petzold & S.S.Brown, 1993, Mutational analysis of yeast profilin. Mol. Cell. Biol., 13:7864-7873.
  • 10Tang, B.L., 2003, Inhibitors of neuronal regeneration:mediators and signaling mechanisms. Neurochemistry International, 42: 189-203.

二级参考文献20

  • 1托尼·赖特 褚松燕等译.《新旧社会主义》[M].北京:新华出版社,2000年版.第162页.
  • 2托马斯·迈尔 殷叙彝译.《社会民主主义的转型》[M].北京大学出版社,2001年版.第41-42页.
  • 3考茨基.《无产阶级专政》(德文版)[M].维也纳,1919年..
  • 4Lain Dale ed , Labor Party General Election Manifestos 1900 - 1997, Routledge, 2000,pp. 54 - 56.
  • 5A Crosland, The Future of Socialism, London. Jonathan Cape, 1956, p. 115.
  • 6A Crosland, The Future of Socialism, p. 75.
  • 7Eric Shaw, The Labor Party since 1979: Crisis and Transformation,London, New York:Routledge, 1994, pp. 2-3.
  • 8Eric Shaw, The Labor Party since 1979 : Crisis and Transformation, p. 2.
  • 9Tudor Jones, Remaking the Labor Party: From Gaitskell to Blair, Routledge, 1996,p. 121.
  • 10Tony Blair,Socialism, Fabian Society, 1994, p. 2.

共引文献1

同被引文献32

  • 1张红云,宋娟娟,刘志刚,康敏雄.芒果果实中泛变应原profilin的克隆、表达及免疫学活性鉴定[J].中华微生物学和免疫学杂志,2007,27(2):111-115. 被引量：8
  • 2Murk K, Buehmeier S, Jockusch B M, et al.. In birds, profilin-2a is ubiquitously expressed and contributes to actin- based motility [J]. J. Cell Sci. , 2009, 122:957 -964.
  • 3Jockusch B M, Murk K, Rothkegel M. The profile of profilins [J]. Rev. Physiol. Biochem. Pharmacol., 2007, 159:131 - 149.
  • 4Witke W. The role of profilin complexes in cell motility and other cellular processes [ J ]. Trends Cell Biol. , 2004, 14 (8) : 461 -469.
  • 5Schluter K, Jockusch B M, Rothkegel M. Profilins as regulators of actin dynamics [J]. Biochim. Biophys. Acta, 1997, 1359(2) : 97 - 109.
  • 6Lai S L, Chan T H, Lin M J, et al.. Diaphanous-related formin 2 and profilin 1 are required for gastrulation cell movements[J]. PLoS ONE, 2008, 3(10) : e3439.
  • 7CarlssonL, Nystrom L E, Sundkvist I, etal.. Actin polymerizability is influenced by profilin, a low molecular weight protein in non-muscle cells[ J]. J. Mol. Biol. , 1977, 115(3) : 465 -483.
  • 8Goldschmidt-Clermont P J, Furman M I, Wachsstock D, et al.. The control of actin nucleotide exchange by thy-mosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cells[J]. Mol. Biol. Cell, 1992, 3 (9) : 1015 - 1024.
  • 9Goldschmidt-Clermont P, Machesky L, Doberstein S, et al.. The actin-binding protein profilin binds to PIP 2 and inhibits its hydrolysis by phospholipase C [ J ]. Science, 1990, 247 (4950) : 1575 - 1578.
  • 10Goldschmidt-Clermont P J, Janmey P A. Profilin, a weak CAP for actin and RAS[J]. Cell, 1991, 66(3) : 419 -421.

引证文献1

二级引证文献2

实验生物学报
2004年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部