经尿道前列腺电切治疗并发膀胱出口梗阻的前列腺癌17例

TRANSURETHRAL RESECTION OF PROSTATE FOR PROSTATIC CANCER WITH BLADDER OUTLET OBSTRUCTION:A REPORT OF 17 CASES

目的 解除前列腺癌所致的膀胱出口梗阻。方法 对 1 7例并发膀胱出口梗阻的前列腺癌患者行内分泌治疗 (睾丸切除术和口服缓退瘤 )及采用经尿道前列腺电切 (TURP)治疗 ,平均随访 2 .3年。结果 电切前列腺组织 (2 0 .3± 8.6) g ,手术前后对比 ,国际前列腺症状评分 (IPSS)由 (2 0 .6± 4 .5)分降至 (7.8± 2 .0 )分 ,最大尿流率 (MFP)由 (6 .5± 4 .0 )ml/s提高至 (1 2 .5± 5 .4)ml/s,前列腺体积(PV)由 (52 .6± 1 5 .0 )g降至 (2 5 .1± 5 .2 ) g。 结论 TURP对前列腺癌致下尿路梗阻者是安全可靠的姑息性治疗方法 ,在有效减少尿路梗阻所致并发症的同时可提高患者生活质量 ,术后前列腺体积减小主要是内分泌治疗的结果。

Objective To relieve bladder outlet obstruction(BOO) caused by advanced prostatic cancer. Methods 17 cases of prostatic cancer with BOO were treated by endocrine therapy and transurethral resection of prostate(TURP),who had been followed up for mean 2.3 years. Results The weight of prostatetissue resected was (20.3±8.6)g,IPSS had been dropped from (20.6±4.5) to (7.8±2.0),the maximum flow rate had been elevated from (6.5±4.0) to (14.5± 4.4 )ml/s,the volume of prostate decreased from (52.6±15.0)g to (25.1±5.2)g. Conclusion TURP is believed to be safe and effective in relieving BOO caused by prostatic cancer so as to improve the life quality.The decrease in prostate volumes is mainly a result of endocrine therapy.