幼儿唾液中的钙含量及其与患龋状况的关系

Relationship between calcium concentrations in saliva of children in healthy and caries status

目的 :探讨幼儿唾液中的离子钙、总钙含量及两者比值与患龋状况的关系。方法 :将 99名 3～ 5岁乳牙列期儿童依据龋患程度分为无龋组、龋病低危组与高危组。采用原子吸收光谱仪 (火焰法 )和离子选择性电极对三组儿童唾液中的总钙含量 (Ca)和离子钙含量 (Ca2 + )分别测定 ,并计算两者比值 (Ca2 + /Ca) ,统计分析此三种指标与患龋状况的关系。结果 :受检乳牙列期儿童唾液中离子钙含量为 (0 .15 8± 0 .0 4 3)mmol/L ,总钙含量 (1.4 36± 0 .30 0 )mmol/L ,离子钙 /总钙含量值为 0 .112。三项指标在性别间无显著性差异(P >0 .0 5 )。唾液离子钙与总钙含量在无龋组、龋病低危组、龋病高危组之间无统计学差异 (P >0 .0 5 ) ,但无龋组的离子钙 /总钙比值高于龋病低危组与高危组 ,有显著性差异 (P <0 .0 5 )。结论 :乳牙列期儿童唾液中离子钙或总钙含量并不能反映个体的龋患状况 ,但离子钙与总钙的比值或可作为评价儿童患龋状况的一个参考指标。

AIM:To investigate the relationship between the concentrations of the ionized calcium(Ca 2+ ) and total calcium(Ca) of stimulated whole saliva in healthy and caries status of 3～5 years o1d children.METHODS:99 children of deciduous denture were enrolled in this study and devided into 3 groups,①caries-free;②caries low-risk;③caries high-risk,according to their dft scores.The Ca 2+ and Ca concentrations of their stimulated saliva were analyzed by atomic absorption spectrophotometry and selective electrode.Comparison of Ca 2+ ,Ca,and Ca 2+ /Ca ratio in 3 groups were analyzed by SPSS(11.0 version).RESULTS:The mean concentration of Ca 2+ in all children′s stimulated saliva was(0.158±0.043)mmol/L and that of Ca was(1.436±0.300)mmol/L,Ca 2+ /Ca ratio was 0.112.No statistical difference was found between sex or in 3 groups of Ca 2+ or Ca concentration( P >0.05),while the Ca 2+ /Ca ratio was significantly higher in caries-free group than caries low-risk or high-risk group ( P <0.05).CONCLUSION:Ca 2+ or Ca concentration of stimulated saliva can not be used alone to evaluate the caries status of children,while Ca 2+ /Ca ratio of stimulated saliva might be useful to indicating the caries status.