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冠状动脉粥样硬化斑块内的炎症反应与CD40信号传导 被引量：3

Inflammation and CD40 Signaling in Coronary Atherosclerotic Plaque
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摘要 冠状动脉粥样硬化斑块内的炎症反应促使冠状动脉内不稳定斑块的形成和破裂 ,在此基础上发生细胞成分的活化并介导血栓形成 ,是绝大多数急性冠状动脉综合征发生的主要原因。近年来的研究发现 ,白细胞分化抗原 40 (CD40 )信号通路参与了动脉粥样硬化斑块内主要细胞成分炎症反应的调节 ,本文对CD40信号与冠状动脉粥样硬化斑块内炎症反应的相关问题作一综述。
作者 蔡伦安 魏经汉 赵洛沙
机构地区 郑州大学第一附属医院心内科
出处 《心血管病学进展》 CAS 2004年第4期283-286,共4页 Advances in Cardiovascular Diseases
关键词 冠状动脉 粥样硬化斑块 炎症反应 CD40信号传导
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献38

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同被引文献21

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  • 9Lutgens E,Daemen MI.CD40-CD40L interactions in atherosclerosis[J].Trends Cardiovasc Med,2002,12(1):27-32.
  • 10Kumanogoh A,Wang X,Lee I,et al.Increase T cell autoreactivity in the absence of CD40-CD40 lignd interaction:A role of CD40 in regulatory T cell development[J].J Immunol,2001,166 (1):353-360.

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心血管病学进展
2004年 第4期

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