板栗花中一个新木脂苷类化合物

A new lignan glycoside from the flower of Castanea mollissima Blume

目的 研究板栗花的活性成分。方法 通过柱色谱进行分离 ,利用波谱数据综合解析鉴定化合物结构。结果 从乙酸乙酯部位得到 5个化合物 ,分别鉴定为杨梅树皮素 (I)、槲皮素 (II)、没食子酸 (III)、4 喹啉酮 2 羧酸(IV)和 (+) 异落叶松树脂醇 9′ O α L 鼠李糖苷 (V)。结论 IV均为首次从板栗花中得到 ,其中化合物V为新化合物 。

Aim To study the bioactive constituents of the flower of Castanea mollissima Blume. Methods Compounds were isolated and purified by column chromatography of silica gel and TLC. Structures were determined by various spectroscopic data, including IR, 1HNMR and 13CNMR, EIMS, FABMS and HMBC as well as comparison of the data with those reported in literatures. Results Five compounds were isolated and elucidated as myricetin (I), quercetin (II), gallic acid (III), 4-quinolinone-2-caboxylic acid (IV), (+)-isolariciresinol-9′-O-α-L-rhamnoside (V). Conclusion These compounds were separated from the flower for the first time and compound V is a new compounds, named chestnutlignansoide.