卵巢外腹膜浆液性乳头状癌的临床诊断与治疗

Clinical diagnosis and treatment of extraovarian peritoneal serous papillary carcinoma

目的 :探讨卵巢外腹膜浆液性乳头状癌 (EPSPC)的临床诊断与治疗。方法 :对 1989年 1月～ 2 0 0 3年 3月收治的、经病理检查证实的 9例EPSPC的临床资料进行回顾性分析。结果 :经采用肿瘤细胞减灭术及术后PC或PAC方案 8个疗程的治疗 ,9例患者中 ,除 1例为术后 1个月 ,4例失访 ,3例死亡 ,1例无瘤生存 4年。结论 :根据病史、临床表现与相关检查 ,EP SPC的术前诊断是可能的 ;肿瘤细胞减灭术与术后化疗可改善预后。

Objective:To investigate the clinical diagnosis and treatment of extraovarian peritoneal serous papillary carcinoma (EPSPC).Methods:Nine cases of EPSPC confirmed by pathologic examination and treated in our hospital from Jan. 1989 to Mar. 2003 were analyzed retrospectively.Results:All patients with EPSPC were given cytoreductive surgery followed by systemic chemotherapy of PC or PAC regimen for 8 courses.Of all patients,4 were not followed up, 3 patients died, one patient was the second month after operation, and one patients disease-free survival time reached 4 years.Conclusion:According to the case history, clinical manifestation and associated examination, pre-operation diagnosis might be possible, and the prognosis may be improved by cytoreductive surgery and adjuvent chemotherapy.