正常眼底不明原因视力异常儿童的眼底荧光造影分析(附4例报道)

The analysis of fundus fluorescein angiography in children with normal fundus and unclear reason abnormal visual acuities

目的 分析眼底荧光血管造影在检测正常眼底、不明原因视力异常儿童患遗传性眼底病变的意义。方法 对 74例 14岁以下儿童患者的眼底荧光血管造影资料进行了回顾性分析。结果 发现有 16例视力异常而眼底检查正常者中 4例FFA显示有遗传性眼底病变 ,其中 2例为Stargardt病 ,1例为视锥细胞营养不良 ,1例为视网膜色素变性。结论 约 2 5 %眼底检查正常、视力有不明原因异常的儿童可能患有某些早期遗传性眼底病变 ;

Objective To evaluate the probability of some kinds of hereditary fundus diseases in children with normal fundus and abnormal visual acuities detected by fundus fluorescein angiography(FFA).Methods The files of FFA in 74 cases of less than 14 years old children were retrospectively analyzed.Results There were 16 cases found with abnormal visual acuities and normal fundus.In them,there were 6 cases of children once diagnosed ametropic amblyopia,but with poor results of therapy.In these 16 cases,4 cases with hereditary fundus diseases were detected by FFA,2 cases were Stargardt′s disease,1 case was cone dystrophy,1 case was retinitis pigmentosa.Conclusions There are about 25% of children with normal fundus and unknown reason decreased visual acuities may be suffered from some kinds of hereditary fundus diseases in early stage.FFA is useful in early diagnosis of those kinds of patients.