核因子-κB与血管成形术后再狭窄

Relationship Between Nuclear Factor-Kappa B and Restenosis after Angioplasty

目的 探讨核因子 kappaB(NF κB)在血管成形术后再狭窄中的作用。方法 对国内、外近 5年的有关文献进行综述。结果 在血管成形术后NF κB可引起平滑肌细胞增生及凋亡减少 ,导致血管内膜过度增生。结论 NF

Objective To discuss the role of nuclear factor kappa B in restenosis after angioplasty.Methods Related literatures of recent 5 years were reviewed.Results Nuclear factor kappa B could lead to hyperplasia of vascular intima which resulted from proliferation and decrease of apoptosis of vascular smooth muscle cells.Conclusion Nuclear factor kappa B plays an important role in restenosis after angioplasty.