健脾纳胃汤治疗糖尿病胃轻瘫80例临床观察

Observation of diabetic gastroparesis treated by Jianpi Nawei decoction

目的 观察健脾纳胃汤治疗糖尿病胃轻瘫的临床疗效和促进胃排空的作用。方法 1 60例糖尿病胃轻瘫患者随机分为 2组。治疗组 80例用自拟健脾纳胃汤治疗 ,对照组 80例用吗丁啉治疗 ,观察 2组患者临床疗效和胃排空情况 ,并在停药后 6个月进行复查。结果 治疗组总有效率为 91 .2 %,对照组为 87.5 %,2组比较无显著性差异 (P >0 .0 5 ) ;治疗后治疗组和对照组胃排空率分别为 ( 83 .9± 2 .7) %和 ( 85 .1± 7.6) %,2组比较无显著性差异 (P >0 .0 5 ) ;停药后 6个月进行复查 ,治疗组复发率为 8.7%,对照组为 61 .6%,2组比较有显著性差异 (P <0 .0 1 ) ;症状积分 2组治疗前后比较均有显著性差异 (P <0 .0 5 ) ,治疗后 2组比较差异不明显(P>0 .0 5 ) 。结论 健脾纳胃汤有治疗糖尿病胃轻瘫和促进胃排空的作用 。

Objective To observe the effect of diabetic gastroparesis treated by Jianpi Nawei decoction. Methods 160 cases with diabetic gastroparesis were randomly divided into control and treatment groups. Patients in control group (n=80) were treated by Motilium. Patients in treatment group (n=80) were treated by Jianpi Nawei decoction. Curative effect index and gastric emptying time were observed for evaluating effect. Reexamination was carried on in 6 months after treatment. Results The total effective rate in treatment group and control group were 91.2% and 87.5%, seperatively. There was no difference between both groups (P>0.05). Results of reexamination showed that recurrent rate in treatment group (8.7%) was markedly lower than that in control group (61.6%, P<0.01). There was difference between symptoms score before and after treatment in both groups (P<0.05). There was no difference between symptoms score control group and treatment group after treatment (P>0.05). Conclusion Jianpi Nawei decoction could treat diabetic gastroparesis and improve gastric emptying time, its effect was durable.