补肾法治疗冠心病心绞痛的临床研究

CLINICAL STUDY ON EFEECTS OF TONIFYING KIDNEY METHODS ON ET、MDA AND CRP LEVELS OF PATIENTS WITH ANGINA PECTORIS

目的 :观察补肾法对冠心病心绞痛的疗效及其对ET、MDA、CRP水平的影响。方法 :10 0例冠心病心绞痛患者随机分成两组 ,治疗组给予补肾中药治疗 ,对照组予单硝酸异山梨酯。同时测定ET、MDA和CRP的变化 ,记录治疗前后心绞痛症状 ,心电图ST -T改变 ,动态心电图缺血性ST -T改变的时间及血粘、血脂情况。结果 :补肾法治疗可明显降低冠心病心绞痛患者的ET ,MDA和CRP水平 ,其临床心绞痛总有效率为 94 % ,心电图改善率为 70 % ,明显缩短心电图缺血性ST -T改变 ,明显改善血粘 ,血脂状况 ,与对照组比较有明显差异。结论 :补肾法对冠心病心绞痛有明显疗效 ,其作用机制可能与降低ET、MDA。

Objective:To observe the effects of tonifying kidney methods on ET,MDA and CRP levels of patients with angina pectoris.Methods:100 cases with angina pectoris were randomly devided into two groups,50 cases were treated with Chinese herbs,the others were given western medicine.ET,MDA and CRP were determined before and after treated,meanwhile recording clinical symptoms,changes of ST-T in ECG,blood viscosity and lipid,etc Results:The levels of ET?MDA and CRP in patients with angina pectoris were significantly higher than normal,the levels were obviously lower in the group with tonifying kidney herbs than before treated and control group.The total effective rate was 94%,the effective rate of ECG improved was 70%,the time of ST-T change was shorter significantly in the treated group.There was obvious difference between Chinese herbs group and western group.Conclusion:Tonifying kidney methods could treat angina pectoris effectively,which may be related to the low of ET?MDA and CRP.