脑梗死中脏腑实验性诊断与神经内分泌免疫网络功能参考指标的研究

Study on apoplexy involving the Zang-Fu organs laboratorial diagnosis and nerve-endocrine-immune network function reference index in cerebral infarction

目的 探讨脑梗死中脏腑与神经内分泌免疫网络 (NEIN)功能在临床诊断上的结合点。方法 用中脏腑实验性诊断参考指标与中脏腑主要证候量值 (风证 )进行相关分析。结果 中脏腑者促肾上腺皮质激素释放激素、促肾上腺皮质激素、皮质醇、免疫细胞因子白细胞介素 - 6、肿瘤细胞坏死因子 5项指标测定值均显著高于中经络和对照组。结论 神经内分泌免疫网络功能测定可作为中脏腑微观辨证或临床实验性诊断参考指标。

Objective It is to discuss the combinative point of apoplexy involving the Zang-Fu organs and the nerve-endocrine-immune network (NEIN) function on clinical diagnosis in cerebral infarction.Methods The laboratorial diagnosis reference index and major syndromic quantitative volume of apoplexy involving the Zang-Fu organs were relatively analyzed.Results The levels of Corticotropin-releasing hormone (CRH), adrenocorticotropic hormone (ACTH), corticosteroid (CS), tumor necrosis factor-arpha (TNFa), interlenkin-6 (IL-6) in patients with apoplexy involving the Zang-Fu organs were markedly higher than those in patients with apoplexy involving the main and collateral channels (P<0.01) and control group (P<0.01).Conclusion The NEIN function determination can be used as microcosmic discriminate and clinical laboratorial diagnosis reference index of apoplexy involving the Zang-Fu organs.