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血管内皮生长因子在老年急性心肌梗死中的作用 被引量:1

The role of vascular endothelia growth factor (VEGF) in senile acute myocardial infarction
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摘要 目的探讨血管内皮生长因子(VEGF)在急性心肌梗死(AMI)中的作用。方法对30例老年AMI患者VEGF进行测定,并与其QRS记分进行相关分析。结果AMI患者的VEGF水平明显升高,统计学有显著差异(P<0.05);AMI患者VEGF水平与QRS记分呈显著负相关(P<0.05)。结论VEGF参与AMI的病理过程,VEGF对AMI患者的预后可能有深远影响。 Objective To investigate the role of vascular endothelia growth factor (VEGF) in senile acute myocardial infarction.Method VEGF was measured in 30 senile patients with AMI, and a related analysis was conducted between the VEGF and the QRS score in them. Results VEGF in patients with AMI was significantly higher (than that in controls)(P<0.05), VEGF in patients with AMI had significantly negative correlation with QRS score(P<0.05). Conclusion VEGF is involved in the pathogenic process in AMI, we can expect the great effect of VEGF on the prognosis in patients in AMI.
出处 《吉林医学》 CAS 2004年第6期31-32,共2页 Jilin Medical Journal
关键词 血管内皮生长因子 急性心肌梗死 QRS记分 Vascular endothelia growth factor Acute myocardial infarction QRS score
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  • 1Nagy JA,Dvorak AM,Dvorak HF.VEGF-A(164/165) and PlGF:roles in angiogenesis and arteriogenesis[J].Trends Cardiovasc Med,2003,13(5):169-175.
  • 2Iwama H,Uemura S,Naya N,et al.Cardiac expression of placental growth factor predicts the improvement of chronic phase left ventricular function in patients with acute myocardial infarction[J].J Am Coll Cardiol,2006,47(8):1559-1567.
  • 3Heeschen C,Dimmeler S,Fichtlscherer S,et al.Prognostic value of placental growth factor in patients with acute chest pain[J].JAMA,2004,291(4):435-441.
  • 4Lenderink T,Heeschen C,Fichtlscherer S,et al.Elevated placental growth factor levels are associated with adverse outcomes at four-year follow-up in patients with acute coronary syndromes[J].J Am Coll Cardiol,2006,47(2):307-311.
  • 5彭雪,李拥军,张辉,杨蓉,王梅,祖秀光,刘素云,刘金明,郝玉明.急性心肌梗死患者血清胎盘生长因子的动态变化[J].中国循环杂志,2008,23(6):415-417. 被引量:3
  • 6刘云峰,王海滨,杨潮萍,李英,王鹏升,赵红英,吕建峰.急性心肌梗死患者血清胎盘生长因子的动态变化及意义[J].河北医药,2010,32(20):2865-2866. 被引量:2
  • 7高润霖.急性心肌梗死诊断和治疗指南[J].中华心血管病杂志,2001,29(12):710-725. 被引量:5018

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