摘要
目的研究国产蛇毒血凝酶(巴曲亭)在骨科手术围术期应用的止血作用。方法选择40例不同种类的骨科手术病人,随机分为巴曲亭组和生理盐水对照组,比较两组病人的术中出血量、术后24h引流量、血红蛋白浓度、输血量、血小板浓度、纤维蛋白原浓度、凝血酶原时间和激活部分凝血酶时间。结果围术期应用蛇毒血凝酶可以显著减少骨科手术的出血量和输血量,但并不影响凝血状态。结论蛇毒血凝酶(巴曲亭)可以作为一种安全、有效的止血剂用于骨科手术。
Objective To study the hemostatic effect of China-made hemocoagulase used perioperatively in orthopaedic surgeries. Methods 40 patients underwent various selective orthopaedic surgeries were selected and randomly allocated to receive hemocoagulase or saline as control. The following data were compared between the two groups:bleeding volume during operation,drainage volume 24h after operation,transfusion volume,haemoglobin,blood platelet,fibrinogen,prothrombin time and activated partial thromboplastin time. Results Hemocoagulase can reduce the bleeding and transfusion volume in orthopaedic surgeries without significant change of coagulation state. Conclusion Hemocoagulase can be used in orthopaedic surgeries as a safe and effective hemostatic agent.
出处
《颈腰痛杂志》
2004年第4期248-250,共3页
The Journal of Cervicodynia and Lumbodynia
