期刊文献+

高同型半胱氨酸血症与青年卒中 被引量:6

Hyperhomocysteinemia and Stroke in Young Adults
下载PDF
导出
摘要 卒中的发病有年轻化的趋势。目前 ,国内外学者都加强了对青年卒中的研究。文章从同型半胱氨酸的代谢、生化特性及其与青年卒中的关系方面阐述了高同型半胱氨酸血症是青年卒中重要的独立危险因素 ,并探讨了可能的机制。 The onset of stroke has a trend of attacking young adults. Scholars both at home and abroad have enhanced their studies on stroke in young adults. This article discusses the hyperhomocysteinemia, which is an independent and important risk factor in young adults with stroke, from its metabolism and biochemical characteristics of homocysteine (Hcy), and explores its possible mechanism.
作者 王娟 张晓琴
出处 《国外医学(脑血管疾病分册)》 2004年第6期445-448,共4页 Foreign Medical Sciences Cerebrovascular Diseases
关键词 高同型半胱氨酸血症 青年 卒中 生化特征 发病机制 homocysteine ■ stroke ■ young adults
  • 相关文献

参考文献28

  • 1McQuillan BM, Beilby JP, Nidorf M, et al. Hyperhomocysteinemia but not the C677T mutation of methylenetetrahydrofolate reductase is an independent risk determinant of carotid wall thickening. The Perth Carotid Ultrasound Disease Assessment Study (CUDAS).
  • 2Vermeulen EG, Rauwerda JA, van den Berg M, et al. Homocysteinelowering treatment with folic acid plus vitamin B6 lowers urinary albumin excretion but not plasma markers of endothelial function or C-reactive protein: further analysis of secondary end-point
  • 3van Dijk RA, Rauwerda JA, Steyn M, et al. Long-term homocysteine-lowering treatment with folic acid plus pyridoxine is associated with decreased blood pressure but not with improved brachial artery endothelium-dependent vasodilation or carotid artery stif
  • 4Vermeulen EG, Niessen HW, Bogels M, et al. Decreased smooth muscle cell/extracellular matrix ratio of media of femoral artery in patients with atherosclerosis and hyperhomocysteinemia. Arterioscler Thromb Vasc Biol, 2001, 21:573 -577.
  • 5Kristensen B, Malm J, Nilsson TK, et al. Hyperhomocysteinemia and hypofibrinolysis in young adults with ischemic stroke. Stroke, 1999,30:974 - 980.
  • 6Selhub J. Homocysteine metabolism. Annu Rev Nutr, 1999, 19:217 -246.
  • 7Yoo JH, Chung CS, Kang SS. Relation of plasma homocyst(e)ine to cerebral infarction and cerebral atherosclerosis. Stroke, 1998, 29:2478 - 2483.
  • 8Ray JG, Harvey DT. Hyperhomocysteinemia as a cause of premature stroke in a young patient. Arch Phys Med Rehabil, 1998, 79:343 - 345.
  • 9Tan NC, Venketasubramanian N, Saw SM, et al. Hyperhomocyst(e)inemia and risk of ischemic stroke among young Asian adults.Stroke, 2002, 33:1956 - 1962.
  • 10Torbus-Lisiecka B, Bukowska H, Jastrzebska M, et al. Lp(a), homocysteine and a family history of early ischemic cerebral stroke. Nutr Metab Cardiovasc Dis, 2001, 11 (Suppl 5): 52 - 59.

同被引文献40

引证文献6

二级引证文献31

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部