摘要
轻度认知功能障碍是正常衰老和痴呆间的一种过渡状态 ,可分为遗忘型和血管型等亚型 ,其概念和诊断正趋向一致。轻度认知功能障碍老年人和痴呆患者在脑脊液Tau蛋白、Aβ、Aβ前体蛋白、胆碱乙酰转移酶活性和事件相关电位等方面有类似变化。文章总结了轻度认知功能障碍的诊断和部分神经生物学指标。
Mild cognitive impairment (MCI) is a transitional stage between normal aging and dementia, which can be divided into amnestic MCI and vascular MCI. They tend to be coincident with their concept and diagnosis. There are similar biological changes in older patients with MCI and Alzheimer's disease, including Tau protein, beta-amyloid protein, amyloid precursor protein, choline acetyltransferase activity and event-related potentials. This article summarizes the latest progress in the diagnosis of MCI and part of neurobiological parameters.
出处
《国外医学（脑血管疾病分册）》
2004年第6期453-456,共4页
Foreign Medical Sciences Cerebrovascular Diseases
