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蛋白酶体抑制剂PS-341在恶性血液病中的研究现状

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摘要 蛋白酶体抑制剂PS-341通过抑制蛋白酶体及NF-κB等机制使肿瘤细胞凋亡,在多发性骨髓瘤等恶性血液病的治疗方而取得了一定的进展。本文就PS-341在恶性血液病中的作用机制、临床疗效及毒副作用作一综述。
出处 《国外医学(输血及血液学分册)》 2004年第4期329-332,共4页 Foreign Medical Sciences(Section of Blood Transfusion and Heanatology)
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