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缺氧缺血性脑损伤与凋亡的进展 被引量：2

Research progress in apoptosis and hypoxic-ischemic brain damage
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摘要 Apoptosis is one of the most important causes, which results in the central neuronal system complication in hypoxic-ischemic brain damage (HIBD). Apoptosis occurs in the developing brain more than in the developed brain. Apoptosis can last several weeks and may be inverted its pathology by appropriate therapy. Caspase inhibitor, neurotrophic factors, anti-apoptosis gene Bcl-2, mild hypothermia,and early intervention play important roles in promoting neuronal cell survival and preventing from apoptosis through different mechanisms. It may be a new way for rehabilitation of HIBD. [ Apoptosis is one of the most important causes, which results in the central neuronal system complication in hypoxic-ischemic brain damage (HIBD). Apoptosis occurs in the developing brain more than in the developed brain. Apoptosis can last several weeks and may be inverted its pathology by appropriate therapy. Caspase inhibitor, neurotrophic factors, anti-apoptosis gene Bcl-2, mild hypothermia,and early intervention play important roles in promoting neuronal cell survival and preventing from apoptosis through different mechanisms. It may be a new way for rehabilitation of HIBD. [
作者 陈敏榕 陈燕惠
机构地区 福建医科大学附属协和医院儿科
出处 《中国病理生理杂志》 CAS CSCD 北大核心 2004年第7期1318-1321,共4页 Chinese Journal of Pathophysiology
关键词 细胞凋亡 缺氧缺血 脑 Apoptosis Hypoxia-ischemia, brain
分类号 R72 [医药卫生—儿科]
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参考文献19

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二级参考文献25

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中国病理生理杂志
2004年 第7期

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