新生儿缺氧缺血性脑病急性期CT改变与预后的关系

The relationship between the brain CT change at acute stage and the prognosis in neonates with HIE

目的 探讨新生儿缺氧缺血性脑病 (HIE)急性期CT改变与预后的关系。方法 对比分析致死、致残组和非残组HIE患儿的特点 ,计算轻、中、重度CT改变 ,估测HIE预后的敏感性、特异性及准确性。结果 6 4例HIE中 ,CT正常 19例 ,CT异常 4 5例 ,其中轻度异常 10例 ,中度异常 16例 ,重度异常 19例。重度CT改变估测HIE预后不良的敏感性、特异性和准确性分别为 6 9.2 3%、97.36 %和 85 .93% ;轻、中度CT改变估测的敏感性不高 ,特异性不强。结论 重度CT改变的HIE患儿发生死亡及残疾的可能性较大 ,应重点观察随访。

Objective To explore the relationship between the brain CT changes at acute stage and the prognosis in neonates with HIE.Methods To analyse the characteristics of death group, disabled group and non-disabled group. To estimate the sensitivity, speciality and accuracy of prognosis in neonates with HIE by calculating the CT changes in mild, middle and severe degree.Result The mortality and the disability in neonates with HIE increased with CT changes from mild dgree to severe degree. The sensitivity, speciality and accuracy of poor prognosis in HIE with severe CT change were respectively 69.23%, 97.36%and85.93%.There were poor sensitivity and speciality of prognosis in neonates with HIE by calculating the CT changes in mild and middle degree.Conclusions There was greater possibility of the mortality and the disability in neonates with HIE in severe degree CT changes. This group should be followed up. [