异位妊娠与宫内妊娠胎盘组织学变化的对比分析

Comparison study of histomorphalogic change of placenta in intrauterine and ectopic pregnancy

目的 :探讨与异位妊娠及宫内妊娠有关的胎盘组织变化并探索和某些与妊娠有关疾病的发生率有关的因素。方法 :对35例异位妊娠及67例宫内妊娠标本常规病理切片进行分指标阅读统计 ,并对结果进行统计学分析 (x2检验 )。结果 :发现在宫内外12种与胎盘组织有关的指标中 ,滋养叶细胞增生及有无蜕膜组织两种指标的差异有显著性 (P<0.05) ,其余10种均无显著性差异(P>0.05)或无差异 ,但均程度不同地存在着在病理形态上容易和某些妊娠滋养细胞肿瘤混淆的因素。结论 :宫内妊娠与异位妊娠在胎盘组织学尤其是绒毛结构上基本一致 ,没有证据表明两者在某些与妊娠有关的肿瘤的发生上存在差异 ,在与妊娠有关的疾病的诊断和鉴别诊断中严格掌握标准并结合临床是重要的。

Objective:To study the histomorphalogic change of placenta in both intrauterine and ectopic pregnancy and possible related facˉtors with pregnancy associated tumors.Methods:The section preparations of placenta in35cases of ectopic pregnancy and67cases of intrauterine pregnancy were observed and a statistic analysises with certain indexes were made(Chi-square test).Results:Among12indexes,only hyperplasia of trophoblastic cell and existence or absence of decidue tissue had statistic significance in differentiation diagnosis(P<0.05)but still existed some confusion factors in differentiation of trophoblastic tumors from pregnancy.Conclusion:The structure of villi is essentially the same in both intrauterine and ectopic pregnancy and also there is no evidence to show any difference between the two kind of pregnancies in the occurrence of pregnancy associated tumors.Following the multiple indexes and combining with clinical data are the key point to make a correct diagnosis for cystomorphology of placenta in both intrauterine and ectopic pregnancy and pregnancy associated tumors.