原发性高血压患者动态血压曲线平滑指数与左室肥厚的关系

Relation between the smooth index of the ambulatory blood pressure curve and left ventricular hypertrophy in the hypertensive patients

目的 :研究反映血压波动程度的新参数曲线平滑指数 (SI)与原发性高血压 (EH)患者左室重量指数(LVMI)的关系。方法 :选择 10 9例EH患者进行 2 4h动态血压监测 ,分析SI、动态血压变异性 (ABPV) ;二维超声测定LVMI ,以男 >12 5、女 >12 0为左室肥厚 (LVH)。结果 :LVH组LVMI、夜间收缩压ABPV(nSABPV)、2 4h收缩压SI(2 4hSIS)、夜间收缩压SI(nSIS)、夜间舒张压SI(nSID)明显高于无LVH组 (P <0 .0 5 ) ;多元逐步回归分析 :LVMI与nSABPV、2 4hSIS、nSIS之间直线相关。结论 :SI可以作为一种反映血压波动的新监测指数 ,其与ABPV联合观察可以更好地反映血压的波动与LVH的关系。

Objective:To evaluate the relation between the smooth index (SI) of the ambulatory blood pressure curve and left ventricular hypertrophy (LVH) in the hypertension. Method:We selected 109 essential hypertensive patients. The blood pressures were measured by ambulatory blood pressure monitoring. SI and the ambulatory blood pressure variability(ABPV) were assayed; The left ventricular mass index (LVMI) was measured by echocardiography. The LVMI in male>125 g/m2 and female>120 g/m2 was defined as LVH's. Result: LVMI, 24 h SIS, nSIS, nSID, nSABPV in LVH group were significantly higher than those in NLVH group. The relation between the 24 h SIS, nSIS, nSABPV and LVMI were correlated. Conclusion: Combination of SI and ABPV can better reflect the relation ship between the blood pressure fluctuation and LVH.