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光度法测定枸橼酸西地那非及尿中西地那非的含量 被引量:2

Spectrophotometric determination of sildenafil citrate and sildenafil in human urine
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摘要 In the condition of pH 2.5~4.7,ethyl eosin reacts with sildenafil to form red ion association complexes.The maximum absorption wavelengths and the maximum fading wavelengths were 550 nm and 520 nm,respectively.The apparent molar absorptivities(ε)were 2.09×104 and 2.44×104L·mol-1·cm-1,respectively.When the dual-wavelength overlapping absorption spectrometry was used to determine the sidenafi,their apparent molar absorptivity ε was increased to 4.57×104 L·mol-1·cm-1.The method was applied to the determination of the content of the agora sell and in human urine sildenafils with satisfactory results. In the condition of pH 2.5~4.7,ethyl eosin reacts with sildenafil to form red ion association complexes.The maximum absorption wavelengths and the maximum fading wavelengths were 550 nm and 520 nm,respectively.The apparent molar absorptivities(ε)were 2.09×10~4 and 2.44×10~4L·mol^(-1)·cm^(-1),respectively.When the dual-wavelength overlapping absorption spectrometry was used to determine the sidenafi,their apparent molar absorptivity ε was increased to 4.57×10~4 L·mol^(-1)·cm^(-1).The method was applied to the determination of the content of the agora sell and in human urine sildenafils with satisfactory results.
出处 《化学研究与应用》 CAS CSCD 北大核心 2004年第4期573-574,共2页 Chemical Research and Application
关键词 光度法 枸橼酸西地那非 尿样 乙基曙红 spectrophotometry sildenafil citrate urine sample ethyl eosin
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  • 1Alex T,J Urol,1998年,160卷,257页

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