摘要
目的 对原发性肺癌经支气管动脉联合胸廓内动脉灌注化疗和单纯支气管动脉灌注化疗进行疗效对比 ,以期对介入治疗肺癌提高认识。方法 对 4 8例经介入疗法治疗原发性肺癌的资料进行回顾分析 ,对联合胸廓内动脉化疗和单纯支气管动脉化疗分组后进行疗效评估。结果 ①联合胸廓内动脉组共 32例 ,其中部分缓解 2 1例 ,稳定 7例 ,进展 4例 ;单纯支气管动脉化疗 16例 ,其中部分缓解 5例 ,稳定 8例 ,进展 3例 ;②化疗后胸背部疼痛及避部皮肤红肿、坏死等副反应在联合胸廓内动脉组 32例中出现 19例 ,在单纯支所管动脉组 16例中出现 4例。结论 ①联合胸廓内动脉组化疗后有效率高于单纯支气管动脉化疗组 ,有统计学意义 ;②联合胸廓内动脉化疗后胸背部疼痛及局部皮肤红肿、坏死等副反应发生率高于单纯支气管动脉组。
ObjectiveTo compare the curative effect of infusion chemotherapy between combined bromchial a rtery with internal thoracic artery a nd bronchial artery only,and so that to improve knowledge on intervene therapy o n lung cancer.Methods Analyzing retrospectively on 48 cases with primary bronchog enic carcinom a treated by intervene therapy,Evaluating the curative effect of intervene thera py between combined bronchial artery with internal thoracic artery and bronchial artery only.Results ①The curative effect of the first group( 32 cases)treated by intervene therapy with combined bronchial artery with internal thoracic artery consisted of 21 cases with partial recovering,7 cases with stability,4 cases with deterior ation;While the curative effect of the second group(16 cases) treated by bronchi al artery only consisted of 5 cases with partial recovering,8 cases with stabili ty,3 cases with deterioration.② There were 19 cases belonging to the first grou p shouing side effects such as pains on chest or the back,swelling or necrosis o n local skin;While only 4 cases treated by intervene therapy via bronchial arter y only suffering from those side effects.Conclusions ①The efficiency rates of intervene therapy betwee n combined bromc hial artery with internal thoracic artery and bronchial artery only were differe nt with statistical significance;②The side effects such as pains on chest o r the back,swelling or necrosis on local skin happened more frequently on patien ts treated by intervene therapy with combined bronchial artery with internal tho racic artery.
