脑梗塞患者红细胞内还原型谷胱甘肽的变化

Glutathione Reduced Form in Erythrocyte of Patients with Cerebral Infarction

红细胞内还原型谷胱甘肽(RBC-GSH)正常参考值5.68～10.34μmol/gHb,脑出血6.72±1.04μmol/gHb,脑梗塞5.02±1.37μmol/gHb。脑梗塞GSH量比正常参考值和脑出血显著减少,有统计学意义(P<0.01)。

RBC-GSH in healthy adult and in patients with cerebral hemorrhage and infarction was determined with DTNB colorimetric method. The concentration of GSH in healthy adults was 5. 68～10.34 nmol/ g Hb, in cerebral hemorrhage was 6.72±1.04μmol/g Hb and in cerebral infarction was 5.02± 1.37 μmol/g Hb. The data obtained show that GSH in patients with cerebral infarction was decreased more markedly than that in heathy adults and cerebral hemorrhage (P<0.01).