水/有机两相体系中芳香腈和脂肪腈的催化加氢反应

Catalytic Hydrogenation of Benzonitrile and Alkyl Nitrile in Aqueous/Organic Biphase System

在水 /有机两相体系中 ,用RuCl3 TPPTS (TPPTSP(m C6H4SO3 Na) 3 )原位反应生成的催化活性物种对苯甲腈进行了催化加氢反应 ,高转化率、高选择性地生成了苯甲醇 .考察了钌浓度 ,P/Ru比 ,反应压力 ,温度和时间等对苯甲腈加氢反应的影响 .其他芳香腈的加氢反应也可高活性、高选择性地进行 ,生成相应的芳香醇 .但是 ,在相同的条件下不发生脂肪腈加氢反应 .反应机理分析表明 ,苯甲腈加氢反应经由苯甲醛生成苯甲醇 .

The hydrogenation of benzonitrile catalyzed by the active species formed \%in-situ\% from RuCl 3-TPPTS (TPPTSP(m-C 6H 4SO 3Na) 3) in aqueous/organic biphase system was studied. Based on the effects of ruthenium concentration, TPPTS/Ru ratio, H 2 pressure, temperature and time on the reaction, the reaction conditions were optimized. The ruthenium catalyst exhibited high activity and high selectivity for benzyl alcohol under the optimum conditions. The conversion of benzonitrile and the yield of benzyl alcohol were more than 99% and 99.5%, respectively. The hydrogenation of benzonitrile derivatives was also carried out with high reactivity and selectivity to form the corresponding derivatives of benzyl alcohol. However, the hydrogenation of alkyl nitrile did not occur under the same reaction conditions. The possible reaction mechanism was suggested.