慢性胃炎的中医辨证分型与胃泌酸功能的关系

Relationship Between TCM Differentiation & Gastric Acid Secretion in Chronic Gastritis

测定62例慢性胃炎患者和10名正常人的基础胃酸和五肽胃泌素刺激后的胃酸分泌量,表明慢性胃炎病人的基础胃液量和胃酸量及激发后的胃液量和胃酸量均明显低于正常人,并与中医实证与虚证分型有关。实证分型中气虚滞湿明显高于气虚瘀湿,气虚滞热和气虚瘀热。虚证分型中肾气虚型略低于脾气虚型。气虚瘀湿型胃酸的激发率高于正常人和其他各型患者,气虚滞热型激发率最低,说明慢性胃炎的宏观中医证与微观的病理生化变化有一定内在联系,这在胃炎的诊断和疗效考核方面有一定的意义。

The secretory volume of gastric juice and acid in the basal state or after the stimula- tion of pentagastrin was determined in 62 cases of chronic gastritis patients and 10 normal persons.The result showed that the secretory volume of gastric juice and acid in the patients under the basal or stimu- lated state is obviously lower than that of normal group and is related to the excess and deficiency syn- dromes in TCM.In the excess syndrome differentiation,the secretory volume of gastric juice and acid in the group.deficiency of Qi with sluggish dampness is significantly higher than that in the groups of def. of Qi with stagnant heat and with sluggish heat.In the deficiency syndrome differentiation,the secretory volume of gastric juice and acid in the group,def.of spleen is slightly higher than that in the group of def.of kidney. The excitation secretion of gastric acid in the patients of the group,def.of Qi with stagnant damp- ness is the highest in the normal and other patient groups,the patients in the group of def.of Qi resulting in sluggish heat is the lowest in the excitation rate of gastric acid.These facts indicated that the macro— syndromes of TCM in chronic gastritis have an internal relation to the micro—changes in pathology and biochemistry.