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HSP70的肿瘤免疫作用及其基因表达调节 被引量:6

Impact of HSP70 on Immunity for Cancer and its Gene Expression Modulation
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摘要 热休克蛋白70能够与肿瘤特异性抗原多肽结合,形成热休克蛋白70鄄多肽复合物,它本身没有抗原性,其抗原性由它结合的多肽所决定,而它是作为“分子伴侣”参与肿瘤免疫作用过程。将这一特性加以应用,可能为肿瘤的治疗和消灭开辟新的途径。 Heat shock protein 70(HSP70) can integrate with antigenic polypeptide with tumor specificity to form heat shock protein 70 and polypeptide compound.HSP 70 perse has no antigenicity.Its antigenicity depends on polypeptide.It participates in the process of immunity for cancer as a'molecular partner'.To make use of this substance might lead to a new approach to cure and toget rid of tumor.
出处 《中国肿瘤》 CAS 2004年第7期430-433,共4页 China Cancer
关键词 热休克蛋白 70 肿瘤 抗原载体 heat shock protein 70 neoplasms and an tigen carrier
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