清轻Ⅰ号胶囊对大鼠脑微血管再通的实验研究

Effects of a Compound Chinese Medicine-QingQing No.Ⅰ on Brain Microvessel in rats

目的 探讨清轻Ⅰ 号胶囊对脑血管痉挛 ,改善微循环的作用。方法 采用大鼠开颅窗、电凝脑微血管的方法观察清轻Ⅰ号胶囊对大鼠脑微循环的影响。结果 清轻Ⅰ 号胶囊组局部动脉电凝后 ,局部动脉管径、血流及毛细血管的变化同对照组相比 ,电凝后 30min ,邻近非电凝的细动脉管径扩张时间长 ,毛细血管血流恢复流动的数量多。本组实验结果与镇脑宁组的结果相近 ,二组之间无明显差别。结论 清轻Ⅰ 号胶囊和镇脑宁对电凝阻断的脑动脉、毛细血管血流有加促恢复的作用 ,能有较好改善大鼠脑软膜微循环的作用。清轻 Ⅰ 号胶囊和镇脑宁对脑软膜微循环的作用结果相似 。

Aim To research the effects of a compound Traditional Chinese medicine-QingQing No.Ⅰ on improving microcirculation of the brain microvessel convulsion.Methods The cerebrate of the rats were opened windows and the blood flow of brain capillary of rats stopped by the electrode(BCE).Effects of QingQing No.Ⅰ on the capillaries of brain were observed under the microscope.Results Compared with the control group,in the group treated the dilating time was longer than that of the part artery of the non-BCE in the near.The diameters of the brain microvessel and the in quantities of the blood capillary recovering blood flows were incneased.There were no obvious difference of the experiment results between the compound Chinese medicine group and the Zhen Nao Ning group.Conclusion The compound Chinese medicine and Zhen Nao Ning both have effects on microcirculation of pia mater membrane of rats,which accelerated recovery of blood flow of blood capillary and improved the microcirculation of pia mater membrane of rats.The two groups do not have the apparent difference.