双能减影与数字X线成像诊断肺内孤立性结节ROC曲线评价

ROC Evaluation of Dual-energy Subtraction vs Digital Radiography in Detecting Solitary Pulmonary Nodules

目的 比较双能减影 (DES)与数字X线成像 (DR)对肺内孤立性结节及结节内钙化的诊断价值。资料与方法 对 4 0例肺内有孤立性结节和 4 0例肺内无孤立性结节的病例行CT、DR及DES检查。 4位医师分别对两组影像学资料进行评价 ,结果采用受试者操作特征 (ROC)曲线进行统计分析。结果 在发现肺内孤立性结节方面 ,DES组的ROC曲线下面积 (Az =0 .94 0 )大于DR组 (Az =0 .891) ,两者统计学具有显著性差异 (P <0 .0 5 ) ;在发现肺内孤立性结节内钙化方面 ,DES组的ROC曲线下面积 (Az=0 .90 2 )大于DR组 (Az=0 .82 8) ,两者统计学具有显著性差异 (P <0 .0 5 )。结论 DES在发现肺内孤立性结节及钙化方面优于DR 。

Objective To compare the value of dual-energy subtraction radiography (DES) and digital radiography (DR) in detecting solitary pulmonary nodule (SPN) and its calcification by using receiver operating characteristic (ROC) curve analysis. Materials and Methods Thoracic CT, DR and DES were performed in 40 patients with SPN and in 40 subjects showing no SPN. The imaging materials of DR group and DES group were separately analyzed by four radiologists. The detection of SPN and the calcification within the lesion was recorded. The results were statistically analyzed with ROC curve.Results For the detection of SPN, the area under ROC curve in DES group (Az=0.940) was larger than that in DR group (Az=0.891), with significant difference between the two (P<0.05). For the detection of calcification within SPN, the area under ROC curve in DES group (Az=0.902) was also significantly larger than that in DR group (Az=0.828) with P<0.05.Conclusion Dual-energy subtraction radiography is superior to digital radiography in detecting both SPN and calcification within the lesion. DES is a useful supplement to DR.