药物睡眠诱发在视频脑电图中的应用价值

Practical value of drug-induced video-EEG in diagnosis

目的 :研究药物睡眠诱发视频脑电图对拟诊癫痫的诊断与分型的价值。方法 :应用伟思 VEEG116 1B型视频脑电图监测对 1 2 5例临床拟诊为癫痫患儿进行常规及药物诱导睡眠诱发脑电图分析 ,并做自身比较。结果 :1 2 5例清醒常规视频脑电图中 ,正常 83例 ,异常 42例 ,占总数 33.6% :其中呈痫样放电 41例。 83例正常者于第 2天进行药物睡眠诱发 ,脑电图正常 35例 ,异常 48例 (痫样放电 47例 ) ,阳性率净增 38.4% ;其中呈中央 -颞区棘波或颞叶棘慢波 1 9例 ,额叶尖棘波 1 2例。结论 :药物睡眠诱发能提高视频脑电图异常率 ,尤其可提高儿童良性癫痫伴中央颞区棘波及额叶癫痫的阳性率。

Objective:To evaluate the practical value of drug-induced video-EEG in diagnosis and typing of childhood epilepsy .Methods:125 child patients with clinically diagnosed epilepsy were monitored routinely by video-EEG(Weisi VEEG 1161B).Among these patients 83 cases with normal routine EEG were monitored with drug-induced video-EEG. Results:Among 125 cases with routine EEG, the EEG was normal in 83 and abnormal in 42 (33.6%) with epileptiform discharges in 41.For the 83 cases with normal routine EEG, drug-induced video-EEG were recorded at the following day. Of them, the drug-induced video-EEG showed normal result in 35 and abnormal in 48(57.8%) with epileptiform discharges in 47. Of the 47 abnormal EEG ,there were centro-temporal spike or temporal spike and wave complex in 19 and frontal sharp wave /spike in 12. Conclusion:Drug-induced video-EEG can increase the positive abnormal rate of video-EEG, especially for benign childhood epilepsy with centro-temporal spikes and frontal epilepsy.