金属支架、内涵管置入术治疗恶性胆道梗阻的费用-效果分析(多中心研究) 被引量：1

The cost-effectiveness analysis of percutaneous transhepatic metal versus plastic biliary stent implantation for treating malignant biliary obstruction (a multi-center investigation)

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摘要目的 :比较金属支架与塑料支架 (内涵管 )置入术治疗恶性胆道梗阻费用效果比。方法 :调查广东省 3家医院 95例实施经皮穿肝胆总管支架置入术的恶性胆道梗阻患者 ,其中 61例置入自膨式金属支架 (支架组 ) ,3 4例置入 10F塑料内涵管 (内涵管组 )。所有患者均回访至死亡或至少术后 1年。用Kaplan Meier方法分析比较两组患者的生存率及支架开通率 ,并计算两组的费用效果比 (CER) ,即中位生存期的CER(CERsp) =总费用 /中位生存期 ,中位开通期的CER(CERpp) =总费用 /中位开通期。结果 :两组总费用分别为 ( 5 3 177± 3 13 9)元和 ( 4 2 5 64± 495 0 )元 ,差异无显著性意义 (P >0 .0 5 )。支架组的CERsp=2 3 7.4元 /天、CERpp=2 3 1.2元 /天 ,低于内涵管组 (分别为CERsp=45 2 .6元 /天、CERpp=472 .9元 /天 )。结论 :金属支架置入术治疗恶性胆道梗阻的费用效果比优于内涵管。 Objective:To compare metal versus plastic biliary stent implantation for treatment of malignant biliary obstruction in cost-effectiveness ratio(CER).Methods:Percutaneous transhepatic self-expandable metal stent (MS,n=61) or 10F plastic stent (PS,n=34) implantation were performed in 95 patients with malignant biliary obstruction in three hospitals of Guangdong province.All patients were followed up until death or at least one year after the procedure.Kaplan-Meier analysis was used to compare patient′s survival and stent patency rates.CERs of two groups were calculated.The main indexes were CER of survival period (total cost/median survival period),CER of patency period (total cost/median patency period).Results:The total costs of treatment were 53177±3139 yuan (RMB) in group MS and 42564±4950 yuan (RMB) in group PS (P> 0.05). CER in group MS was superior to that in group PS (CER of survival period was 237.4 yuan /d vs 452.6 yuan /d,respectively;CER of patency period was 231.2 yuan/d vs 472.9 yuan/d,respectively).Conclusion:The metal stent implantation is superior to the plastic stent in the CER for treatment of malignant biliary obstruction.

作者郭元星李彦豪陈勇陈平雁罗鹏飞李勇单鸿姜在波

机构地区第一军医大学附属南方医院介入治疗科第一军医大学统计教研室广东省人民医院肿瘤介入科中山医科大学附属第三医院肿瘤介入科

出处《放射学实践》 2004年第7期467-470,共4页 Radiologic Practice

关键词金属支架内涵管置入术恶性胆道梗阻费用-效果分析腹腔转移 Radiology,interventional Stents Biliary obstruction Cost-benefit analysis

分类号 R735 [医药卫生—肿瘤]

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