中西医结合治疗改善强直性脊柱炎患者疼痛及关节活动度的效果

Effects of combined treatment of traditional Chinese medicince and western medicine to ameliorate pains and joint motion of patients with ankylosing spondylitis

目的:探讨中药对强直性脊柱炎患者治疗的效果。方法:采用随机、对照的实验研究的方法,对50例强直性脊柱炎患者分成治疗组(30例)和对照组(20例),治疗组给予盐酸青藤碱片(正清风痛宁)和柳氮磺胺吡啶治疗,对照组单用柳氮磺胺吡啶治疗。结果:治疗组有效26例,对照组有效14例;治疗组疼痛、回压4字征、肿胀、活动度和晨僵改善明显优于对照组,差异有显著性意义(χ2=51.95～60.32,P均<0.01);治疗组治疗后手指地面距离、枕墙距离、髋关节前屈、髋关节后伸均优于治疗前,差异有显著性意义(t=2.11～2.91,P<0.05～-0.01)。结论:中药正清风痛宁对强直性脊柱炎的治疗效果明显。

AIM: To study the therapeutic effect of traditional Chinese medicine on patients with ankylosing spondylitis. METHODS:Randomized controlled experiment was carried out. A total of 50 patients with ankylosing spondylitis were divided into treatment group (n=30) and control group (n=20).Patients in treatment group received hydrochloric acid cucoline sheet(zhengqing fengtongning) and salazosulfadimidine, while patients in the control group only received salazosulfadimidine. RESULTS:Twenty six cases was effective in the treatment group and fourteen in the control group:improvement in pain,tender,swelling,activity,morning stiffness in the treatment group was obviously better that that in the control group, which indicated significant difference(χ2=51.95-60.32,all P< 0.01);distance between figures and ground,distance between occipital bone and wall,coxa joint anteflexion, coxa postextension in the treatment group after treatment were better than those before treatment, which showed significant difference(t=2.11-2.91,P< 0.05-0.01). CONCLUSION:Zhengqing fengtongning has significant treatment effect on ankylosing spondylitis.