宫颈癌根治术中卵巢移位的价值

Evaluation of Transposed Ovaries in Cervical Cancer Patients After Surgery and Pelvic Irradiation

背景与目的 :探讨宫颈癌根治术中卵巢移位的价值。材料与方法 :对75例45岁以下Ia2～IIb早期宫颈鳞癌患者于根治术中行单侧或双侧卵巢移位 ,通过血清性激素水平测定和超声检测等方法评估移位术后卵巢功能。结果 :卵巢移位术安全可靠 ,单侧或双侧卵巢移位后均无移位卵巢发生癌转移现象 ;移位后未辅加放疗组卵巢功能无明显变化 ,辅加放疗组雌、孕激素水平虽较未放疗组减低 ,但仍显著高于根治性放疗组。结论 :45岁以下宫颈癌患者根治术中保留卵巢安全有效 ,可显著提高患者雌、孕激素水平。

BACKGROUND&AIM: To evaluate the value of transposed ovaries in cervical cancer patients after surgery and pelvic irradiation. MATERIAL AND METHODS: In75patients with stage Ia 2 ～IIb cervical cancer,24～45years of age,Wertheim_Meigs radical hysterectomy was performed with preservation of one or both ovaries transposed outside the pelvis.For evaluation of the post_treatment hormonal function of gonads,serum FSH,LH,estradiol and progesterone levels were assayed after irradiation. RESULTS: The method of transposed ovaries is safety and effecˉtive.No patients with retained ovaries developed metastatic disease.The patients who postoperative radiotherapy be indicated occur a substantial loss of ovarian function,but the levels of estradiol and progesterone significantly higher than in the radical therapy group. CONCLUSION: It is our opinion that normal ovaries can be preserved in the women under the age of45years at the time of radical hysterectomy for stage Ib～IIb cervical cancer.