上海市原发性肝癌流行状况和趋势分析

Epidemiologic trends and patterns of primary liver cancer in shanghai

目的通过对肿瘤登记资料的分析,了解上海市原发性肝癌的发病状况和变化趋势。方法对1972鄄2001年上海市区居民及1998鄄2001年上海全市居民肿瘤登记,统计分析原发性肝癌发病的时间趋势、人群分布和地理分布。采用国际疾病分类ICD鄄9登记病例进行编码。用世界标准人口对发病率进行标化。用直线回归拟合估计平均年变化量(AAPC)。结果过去的30年中,市区居民不论性别原发性肝癌标化发病率都呈下降趋势。1998鄄2001年全市男性平均年发病率为39.86/10万,女性为16.45/10万。男性占所有肝癌发病的71.06%。全市居民的原发性肝癌发病率随年龄增长而升高。在地理分布上郊县最高,郊区其次,市区最低。结论原发性肝癌的流行状况为评价肝癌预防措施的效果提供有益的参考。

Objective To determine the trends and patterns of primary liver cancer in Shanghai based on the data from Shanghai Cancer Resistry. Methods The data were collected from the urban population in 1972-2001, and from the whole population in Shanghai in 1998-2001. The registered cases were coded by ICD-9. The standardized incidence rates were calculated with the world standard population. Average annual percent changes (AAPC) were estimated by means of linear regression of the logarithm of the incidents rates on calendar year. Results As analysis on the epidemiologic trrends of primary liver cancer in Shanghai was made. During the past 30 years, the standardized incidence rate in both genders decreased significantly in urban population. During the period 1998-2001, in the whole population, the average incidence rate per year was 39.86/100 000 for the male and 16.45/100 000 for the female; male cases accounted for 71.06% of the series. The incidence rate went up wards with age in both genders. Geographic analysis showed that the incidence rate was the highest in the countryside, ranked second in the suburbs, and the lowest in the urban area. Conclusions The trends and the patterns of primary liver cancer in Shanghai provided important help to the adoption of appropriate preventive measures.