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儿童急性淋巴细胞白血病MTHFR基因多态性分析 被引量:9

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出处 《中华血液学杂志》 CAS CSCD 北大核心 2004年第7期439-440,共2页 Chinese Journal of Hematology
基金 国家自然科学基金资助项目 (3 0 0 70 795 )
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  • 1Skibola CF, Smith MT, Kane E, et al. Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults. Proc Natl Acad Sci U S A,1999,96 : 12810-12815.
  • 2Wiemels JL, Smith RN, Taylor GM, et al. methylenetetrahydrofolate reductase(MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia. Proc Natl Acad Sci U S A, 2001,98:4004-4009.
  • 3Pepe G, Vanegas OC, Giusti B, et al. Heterogeneity in world distribution of the thermolabile C677T mutation in 5,10-methylenetetrahydrofolate reductase. Am J Hum Genet, 1998, 63:917-920.
  • 4Rosenberg N, Murata M, Ikeda Y, et al. The frequent 5,10-methylenetetrahydrofolate reductase(MTHFR) polymorphisms is associated with a common Haplotype in Whites, Japanese, and Africans. Am J Hum Genet, 2002,70:758-762.
  • 5Blount BC, Mack MM, Wehr CM, et al. Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage. Proc Natl Acad Sci U S A, 1997, 94:3290-3295.
  • 6Skibola CF, Smith MT, Hubbard A, et al. Polymorphisms in the thymidylate synthetase and serine hydroxymethyltransferase genes and risk of adult lymphocytic leukemia. Blood, 2002, 99:3786-3791.

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