期刊文献+

胰蛋白酶原激活肽在急性胰腺炎早期诊断中的应用

Application of trypsinogen activation peptide in the early diagnosis of acute pancreatitis
下载PDF
导出
摘要 急性胰腺炎发病机理的中心环节是胰腺组织受胰蛋白酶的自身消化作用 ,对其周围组织的消化 ,从而继发一系列的器官功能障碍。胰蛋白酶原激活肽 (TAP)是胰蛋白酶原激活后释放出来的短肽 ,可以很快进入腹膜、血液及尿液。检测体液TAP浓度 ,可以特异地反映胰蛋白酶原激活情况以及早期预测急性胰腺炎患者病情严重程度 。
作者 王慧 徐霞
出处 《国外医学(临床生物化学与检验学分册)》 2004年第4期311-312,315,共3页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
  • 相关文献

参考文献10

  • 1Khan Z,Vlodov J,Horovitz J,et al.Urinary trypsinogen activation peptide is more accurate than hematocrit in determining severity in patients with acute pancreatitis:a prospective study.Am J Gastroenterol,2002,97(8):1973-1977.
  • 2Foitzik T,Fernandez-del-Castillo C,Lewandrowski KB,et al.Trypsinogen activation peptides in acute pancreatitis.Experimental data and clinical implications.Chirurg,1994,65(3):186-189.
  • 3Lerch MM,Kruger B,Tessenow W,et al.Role of protease activation in pathophysiology of acute pancreatitis.Langenbecks Arch Chir Suppl Kongressbd,1998,115:421-426.
  • 4Kemppainen E,Mayer J,Puolakkainen P,et al.Plasma trypsinogen activation peptide in patients with acute pancreatitis.Br J Surg,2001,88(5):679-680.
  • 5Hofbauer B,Saluja AK,Bhatia M,et al.Effect of recombinant platelet-activating factor acetylhydrolase on two models of experimental acute pancreatitis.Gastroenterology,1998,115(5):1238-1247.
  • 6Halangk W,Lerch MM,Brandt-Nedelev B,et al.Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis.J Clin Invest,2000,106:773-781.
  • 7Whitcomb DC.Hereditary pancreatitis:new insights into acute and chronic pancreatitis.Gut,1999,45(3):317-322.
  • 8Tenner S,Fernandez-del-Castillo C,Warshaw A,et al.Urinary trypsinogen activation peptide (TAP) predicts severity in patients with acute pancreatitis.Int J Pancreatol,1997,21(2):105-110.
  • 9Triester SL,Kowdley KV.Prognostic factors in acute pancreatitis.J Clin Gastroenterol,2002,34(2):167-176.
  • 10史海安.进一步提高重症急性胰腺炎的研究水平[J].中华实验外科杂志,1999,16(3):194-194. 被引量:1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部