多巴胺、酚妥拉明佐治新生儿硬肿症30例

Observation on auxiliary treatment of sclerederma neonatorum with dopamine and phentolamine

目的:观察多巴胺、酚妥拉明对新生儿硬肿症的治疗效果。方法:将56例新生儿硬肿症随机分为常规组和治疗组。治疗组在常规治疗基础上佐以多巴胺、酚妥拉明。结果:治疗组总有效率93.3%,优于常规组69.2%,两组比较,χ2=7.04,P<0.01;皮肤硬肿消退时间治疗组(3.75±1.64)d,常规组(4.88±1.93)d,两组比较t=3.027,P<0.01。结论:在常规治疗基础上加用多巴胺、酚妥拉明治疗是新生儿硬肿症有效治疗方法之一。

Objective: To investigate the effect of dopamine and phentolamine on the scleredema neonatorum. Methods: 56 patients were divided randomly into routine group and treatment group. The treatment group was treated with dopamine and phentolamine besides the routine therapy. Results: Therapeutic effectiveness in the treatment group (93.3%) was better than the routine group (69.2%), χ2=7.04, P < 0.01; the duration of cutis sclerosis in the treatment group (3.75±1.64 day) was shorter than in the routine group (4.88±1.93 day), t=3.027, P < 0.01. Conclusion: It is a effective method to use dopamine and phentolamine besides the routine therapy for scleredema neonatorum.