纳米细菌与冠心病

Nanobacteria and Coronary Heart Disease

最近新发现的纳米细菌是目前已知的最小的细菌 ,其直径为几十至几百纳米。与其它细菌不同 ,它们是一种生长繁殖缓慢 ,能通过普通滤菌器 ( 0 .2um) ,具有生物矿化作用和一定抗辐射能力 ,革兰氏染色阴性的球形细菌。它们最特殊的生物学特性是可以在生理状态的钙、磷浓度下分泌主要由羟磷石灰碳酸盐构成的保护性外壳。因此 ,它们被认为与机体内病理性钙化密切相关。近年来研究发现 ,它们可能是冠心病的一种感染性致病源。抗纳米细菌治疗的临床实验显示在冠心病患者中具有一定疗效。

Nanobacteria discovered recently are smallest bacteria as we know now, whose diameter are tens or hundreds nanometer. They are a kind of mineral-forming, sterile-filterable, slow-growing, radio-resistant and Gram-negative bacteria. Their most remarkable characteristic is forming a hard protective shelter made of carbonate apatite crystals at physiologic phosphate and calcium concentrations. They are thought to play an important part in the process of pathologic calcification. Resent researches demonstrate that nanobacteria may be a novel infectious agent of coronary heart disease. Anti-nanobacteria therapy has shown potential positive effect in some clinical experiments.