韦氏环原发性非霍奇金淋巴瘤误诊分析

Analysis on misdiagnosis of primary non-Hodgkin's lymphoma in Waldeyer's ring

目的 :探讨韦氏环原发性非霍奇金淋巴瘤 (NHL)临床和病理误诊的原因和避免误诊的措施。方法 :回顾性分析我院近 10年来韦氏环原发性非霍奇金氏淋巴瘤 92例患者的临床资料。结果 :92例韦氏环原发性NHL中临床误诊 18例 ,病理误诊 72例 ,1临床和病理均误诊的有 18例 ,平均每例病理误诊约 2～ 3次。误诊疾病为慢性扁桃体炎、扁桃体肥大、咽炎、淋巴组织增生等。全部 72例最后经病理确诊为非霍奇金淋巴瘤。结论 :韦氏环原发性非霍奇金淋巴瘤临床特征缺乏特异性 ,病理表现复杂 。

Objective:To study the cause of clinical and pathological misdiagnosis and the measures against misdiagnosis in cases with primary non-Hodgkin's lymphoma in Waldeyer's ring.Methods:The clincal data of ninty two patients with primary NHL in Waldeyer's ring admitted to our hospital in recent ten years were studied retrospectively.Results:Eighteen patients were misdiagnosed clinically and seventy two patients were misdiagnosed pathologically.18 cases were misdiagnosed both clinically and pathologically, with the average misdiagnosis rate of 2～3 times per case.The misdiagnosed diseases were chronic tonsillitis,tonsil vegetation,pharyngitis,lymphatic tissue hyperplasia,etc.All seventy-two patients were diagnosed as NHL finally.Conclusion:The patients with the primary NHL in Waldeyer's ring lack characterisic symptoms.Pathological manifestation is complicated.It is important to do biopsy exactly and diagnose early by immunohistochemical approaches.