Ⅰ期子宫内膜癌68例预后因素分析

Prognosis Analysis of 85 Cases with Stage Ⅰ Endometrial Carcinoma

目的 分析Ⅰ期子宫内膜癌患者的预后相关因素。方法 对 85例Ⅰ期子宫内膜癌患者的治疗随访 ,卡方检验进行统计学分析分析。结果 5年总生存率为 90 6%,存活率在Ⅰa期 10 0 %、Ⅰb期 90 2 5 %、Ⅰc期 82 41%,Ⅰa与Ⅰc相比有显著性差异 ;在子宫内膜样腺癌中 94 0 3 %、非子宫内膜样癌中 77 78%,两者相比有显著性差异 ;在组织学分级中G1 95 45 %、G2 95 2 4%、G3 75 0 0 %,G1 与G3 相比有显著的差异 ,在给予激素治疗中 94 83 %、未给予激素治疗中 81 48%、两者相比有显著性差异 ;在手术方式中全子宫双附件中 92 5 0 %、宫体癌根治术中 88 3 7%,两者相比无显著性差异。结论 Ⅰ期子宫内膜癌手术方式的选择并不影响预后 ;手术病理分期、病理类型。

Objective To analyze the prognosis factors of endometrial carcinoma stage Ⅰ.Methods All 85 patients were treated and followed up in our hospital.The survival was calculated by κ 2 (Kaplah_Meier) method.Results The overall 5 year survival rate was 90 6%,stage Ⅰa 100%,stage Ⅰb 90 25%,stage Ⅰc 82 41%.There was a significant difference?between Ⅰa and Ⅰc.The survival in endometrial adenocarcinoma 94 03%,which indicated a significant different compared with non_endometrial adenocarcinoma 77 78%;The survival rate in histologic grade was G 1 95 45%,G 2 95 24%,G 3 75 00%.There was a significant difference between G 1 and G 3.The survival rate in patients who were treated with progestins 94 83% was significantly higher than that of patients not treated with progestints 81 48%.The survival rate displayed no significant difference between patients treated by total abdominal hysterectomy with bilateral salpingo_oophorectomy and those treated by radical hysterectomy and pelvic lymphadenectomy.Conclusions The operation types had not affected prognosis of endometrial carcinoma stage Ⅰ.Prognosis factors included surgical stage,histological type,histological grade,hormone therapy.