漳州市健康人群定量超声骨量峰值研究

Studies on peak bone density in Zhangzhou Area

目的 研究漳州市健康人群骨量峰值,为原发性骨质疏松症的诊断和预防提供参考数据。方法 2000年2月-2003年2月我们采用超声骨密度仪对居住漳州市5年以上的300名健康人,年龄为25-49岁,男女各150例,以5岁为一年龄组,共5组,每组30人,测量跟骨超声振幅衰减(BUA),超声声速(SOS)及刚度(STT)。结果 漳州市健康人群男、女性的BUA,SOS及STT的峰值均在35-39岁年龄段,各年龄组均随年龄增长而见先递增再递减的变化,男性均高于女性,但差异无显著性。男性35-39岁年龄组与45-49岁年龄组差异有显著性。女性在45-49岁年龄组与35-39岁年龄组比较差异有非常显著性,与其他组差异有显著性。结论 定量超声骨密度仪分析骨密度具有一定临床和科研价值,漳州市骨量峰值与国内相关研究基本一致。

Objective To study the peak bone density in normal subjects, providing useful data for diag-nosis and prevention of osteoporosis. Methods Calcaneal parameters, including broadband ultrasound attenuation (BUA) , speed of sound (SOS) , and stiffness (STI) were measured in 300 normal subjects in Zhangzhou, aged 25 to 49 (150 women and 150 men) ,with UBIS 3000 QUS (made in France) . They were divided into 5 age groups by every five years. Results The peak values of BUA, SOS and STI of the calcaneus appeared all in 35-39 years for men and women. The BUA, SOS and STI in both men and women changed with increasing age. The BUA, SOS and STI values in men were greater than those in women in different ages. The BUA, SOS and STI were different between the 35-39 group and the 45-49 group ( P < 0.05). Conclusion Ultrasonography is useful in detection of bone density and clinical study of osteoporosis. The results of this study are similar to those in other cities in China.